Human coagulation Factor XII

Human Factor XII is a single chain glycoprotein prepared from fresh human plasma by ion exchange chromatography. Factor XII is converted, principally from the action of kallikrein, into an active serine protease Factor alpha-Xlla that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. Purity of Factor XII is >95percent by SDS-PAGE and activity is determined via clotting assay. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD Creutzfeldt-Jakob Disease.

Storage temperature: -70 C
Transport temperature: Dry ice
Supplier: Molecular Innovations