Single Chain High MW Kininogen

HK 1300 Single Chain High Molecular Wt. Kininogen (Fitzgerald Factor)High Molecular Weight Kininogen (HK) is a nonenzymatic cofactor of the contact activation system. HK is thought to have two functions in the contact activation system. First, HK links prekallikrein to a negatively charged surface thereby allowing activation to kallikrein by surface bound Factor -Xlla. HK also forms a complex with Factor XI and accelerates its activation to XIa by -Xlla. Also HK serves as a source of Bradykinin, a potent Vasoactive peptide important in hypotension studies. The protein purity is determined by SDS-PAGEBuffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3*Extinction Coefficient (1%) = 7.01Molecular Weight = 120,000 daltons

Size: 1 mg
Source: Human
Storage temperature: 2-8C
Transport temperature: 2-8C

Delivery time: 2-14days

Supplier: Enzyme Research