Recombinant Rat MIP-1 Beta (CCL4) Protein

Both MIP-1&alpha and MIP-1&beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1&alpha and MIP-1&beta exert similar effects on monocytes their effect on lymphocytes differ with MIP-1&alpha selectively attracting CD8+ lymphocytes and MIP-1&beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1&alpha and MIP-1&beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1&alpha and MIP-1&beta are active on human and murine hematopoietic cells. Recombinant rat MIP-1&beta is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Size: 20ug
Source: E. Coli
Application: Cell Culture
Storage temperature: Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio