Non-enzymatic non-cleavable Human tPA

Human tPA with a double mutation that is permanently single chain and lacks catalytic activity. The non-catalytic mutation site is S478A on the mature protein and S513A on the complete mRNA sequence UniProtKB: locus TPA_HUMAN, accession P00750. The non-cleavable mutation site is R275E on the mature protein and R310E on the complete mRNA sequence UniProtKB: locus TPA_HUMAN, accession P00750. Recombinantly produced in insect cells.

Storage temperature: -70 C
Transport temperature: Dry ice
Supplier: Molecular Innovations