LULLABY siRNA TRANSFECTION REAGENT SAMPLE

Lullaby is the ideal siRNA transfection reagent for gene silencing. Relying on the TEE-technology, it has been successfully tested on numerous cell lines, reaching up to 90% gene silencing with high reproducibility and a very low toxicity. RNA interference is a powerful technique to shut down genes expression in cells and organisms. This silencing effect constitutes a very helpful tool to study genes function and a promising approach for new therapeutic treatments. Short RNA duplexes (siRNA: small interfering RNA, shRNA: small hairpin RNA and dsRNA: double strand RNA) are extremely selective by interacting and inducing the degradation of their specific mRNA targets and thereby inhibit the resulting protein production. Lullaby siRNA Transfection Reagent introduces the siRNA duplexes in a variety of cells with a very high efficiency leading to exceptional knockdown effects with low doses of siRNA. We initially collated a transfection reagent library of 26 reagents...By far, our preferred reagent is Lullaby from OZ Biosciences. We have used this reagent in over 20 cell lines and have found it essential in enabling siRNA screens in hard to tranfect cell lines..., with minimal toxicityEmma L. Shanks (2014) Strategic siRNA Screening Approaches to Target Cancer at the Cancer Research UK Beaston Institute, Combinatorial Chemistry & High Throughput Screening, 17:328-332

Size: 50µL
Storage temperature: 4C
Transport temperature: RT

Delivery time: 2-14days

Supplier: OZ Biosciences SAS