Factor XIIa

HFXIIa 1212a Human Factor XIIa (Activated Hageman Factor)Human Factor -XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. ERL offers Factor -XIIa which is activated by the autoactivation process with Dextran Sulfate and re-purified to remove the activator. The protein purity is determined by SDS-PAGE and activity is determined via clotting assay.Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3*Extinction Coefficient (1%) = 14.1Molecular Weight = 80,000 daltonsAlso available: Human Factor XIIa beta

Size: 0,5 mg
Source: Human
Storage temperature: 2-8C
Transport temperature: 2-8C

Delivery time: 2-14days

Supplier: Enzyme Research