Anti-Notch1 Monoclonal Antibody

Rabbit Monoclonal Notch1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse. Size: 100ug.

Size: 100ug
Source: Mouse
Reactivity: Human, Mouse
Purity: Affinity-chromatography
Application: IF, IHC, WB
Immunogen: A synthesized peptide derived from human Notch1 Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.
Clonality: Monoclonal
Storage temperature: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio