Anti-APC Monoclonal Antibody

Rabbit Monoclonal APC Antibody. Validated in IP, IF, IHC, WB and tested in Human, Rat. Size: 100ug.

Size: 100ug
Source: Rabbit IgG
Reactivity: Human, Rat
Purity: Affinity-chromatography
Application: IP, IF, IHC, WB
Immunogen: A synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Clonality: Monoclonal
Storage temperature: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio