Recombinant Human TNF-Beta (E.coli-derived) Protein

TNF-&beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-&beta is produced by activated T and B lymphocytes, and has similar activities to TNF-&alpha. Like TNF-&alpha, TNF-&beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-&beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-&beta, which effectively anchors the TNF-&beta to the cell surface. TNF-&beta is cytotoxic to a wide range of tumor cells. Recombinant human TNF-&beta is a secreted 171 amino acid protein (18.6 kDa) which forms an active non-disulfide linked homotrimer structure in solution.

Size: 20ug
Source: E. Coli
Application: Cell Culture
Storage temperature: Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio