Recombinant Human IL-36 Beta (IL-1F8) Protein

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36&alpha (IL-1F6), &beta (IL-1F8) and &gamma (IL-1F9). IL-36&beta is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36&beta signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36&beta also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36&beta is a 17.3 kDa protein containing 154 amino acid residues.

Size: 10ug
Application: Cell Culture
Storage temperature: Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio