Anti Human VLDL receptor, clone 1H10

Monoclonal antibody produced in mouse. Useful for ELISA and western blot under non-reducing conditions. Binds to an epitope on the C-terminus of VLDL receptor ligand binding domain amino acids 191-355, UniProtKB: locus VLDLR_HUMAN, accession P98155 and blocks apoE4 binding. Purified by immobilized Protein A. IgG1 class.
References:
Functional domains of the very low density lipoprotein receptor: molecularanalysis of ligand binding and acid-dependent ligand dissociationmechanisms. Mikhailenko I et al. Journal of Cell Science 112, 3269-3281 1999.
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. Ruiz J et al. Journal of Lipid Research 46, 1721-1731 2005.

Storage temperature: -70 C
Transport temperature: Dry ice
Supplier: Molecular Innovations