Anti-Chemokine Receptor D6 Antibody

Polyclonal antibody for ACKR2 detection. Host: Rabbit.Size: 100&mul. Tested applications: WB. Reactive species: Human. ACKR2 information: Molecular Weight: 43443 MW Subcellular Localization: Early endosome. Recycling endosome. Cell membrane Multi-pass membrane protein. Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via clathrin-coated pits. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane Tissue Specificity: Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors. Expressed at high levels in Kaposi sarcoma-related pathologies. Expressed on apoptotic neutrophils (at protein level). Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node.

Size: 100ul
Source: Rabbit
Reactivity: Human
Purity: Immunogen affinity purified
Application: WB
Immunogen: Synthesized peptide derived from the C-terminal region of human Chemokine Receptor D6. at AA rangle: 310-390
Storage temperature: Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio