Anti-Atrophin-1 Antibody

Polyclonal antibody for ATROPHIN 1/ATN1 detection. Host: Rabbit.Size: 100&mul. Tested applications: WB. Reactive species: Human. ATROPHIN 1/ATN1 information: Molecular Weight: 125414 MW Subcellular Localization: Nucleus. Cytoplasm, perinuclear region. Cell junction . Shuttles between nucleus and cytoplasm. Colocalizes with FAT1 in the perinuclear area, at cell- cell junctions and leading edges of cells (By similarity). Colocalizes with MTG8 in discrete nuclear dots. Proteolytic fragment F1 appears to remain in nucleus. Fragment F2 is exported into the cytoplasm. Fragment F2 from mutant sequences with longer poly-Asn (polyQ) tracts are additionally located to the cytoplasmic membrane and to certain organelles Tissue Specificity: Widely expressed in various tissues including heart, lung, kidney, ovary, testis, prostate, placenta, skeletal Low levels in the liver, thymus and leukocytes. In the adult brain, broadly expressed in amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus, and thalamus. High levels in fetal tissues, especially brain.

Size: 100ul
Source: Rabbit
Reactivity: Human, Mouse, Rat
Purity: Immunogen affinity purified
Application: WB
Immunogen: Synthesized peptide derived from the N-terminal region of human Atrophin-1. at AA rangle: 50-130
Storage temperature: Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.
Transport temperature: Shipped with wet ice

Supplier: Bosterbio